Anti-P2RX3 Antibody

The P2RX3 protein is an ATP-gated cation channel belonging to the P2X family of purinergic receptors, and this rabbit polyclonal IgG reagent from Antibodies.com is raised against it for Western blot detection in rat samples. P2RX3 is preferentially expressed in small-diameter sensory neurons of the dorsal root and trigeminal ganglia, where it mediates ATP-evoked currents linked to nociceptive signaling, and it has been studied in models of neuropathic, inflammatory, and visceral pain. The unconjugated antiserum is supplied as 200 µl, suitable for immunoblotting of tissue lysates and cultured sensory neuron preparations. Confirmed rat reactivity supports ion-channel expression studies in rodent pain pathways. For research use only; not intended for diagnostic or therapeutic applications.