Anti-p21 Antibody

The Antibodies.com Anti-p21 polyclonal reagent is a rabbit-hosted primary antibody raised against the cyclin-dependent kinase inhibitor p21 (CDKN1A), a key regulator of the G1/S cell cycle checkpoint and downstream effector of p53-mediated DNA damage response. Produced as an unconjugated IgG preparation and supplied in a 100 µl vial of ready-to-use reagent, it is validated for Western blot and ELISA workflows across human, mouse, and rat sample types. Researchers commonly deploy this reagent to monitor p21 upregulation following genotoxic stress, to distinguish senescent cell populations, and to profile cell cycle arrest in tumor suppressor studies. The polyclonal format increases the likelihood of recognizing multiple epitopes on the target, which is useful when probing post-translationally modified or truncated p21 species that may be missed by monoclonal alternatives. Aliquot upon first thaw and store refrigerated to preserve activity across repeated experiments.