Anti-p16 ARC Antibody

This recombinant rabbit monoclonal antibody targets p16-ARC, a 16 kDa subunit of the seven-subunit Arp2/3 complex that nucleates branched actin filament networks at the leading edge of migrating cells. Provided by Antibodies.com as an unconjugated reagent in a 100 µl vial, it is validated for Western blot, immunocytochemistry/immunofluorescence, immunohistochemistry, and flow cytometry, and it cross-reacts with human, mouse, and rat samples, supporting comparative studies of cytoskeletal remodeling in both cultured cell lines and primary tissue. Each preparation is supplied in TBS buffer at pH 7.4 with 1% BSA, 40% glycerol as a cryoprotectant, and 0.05% sodium azide as a preservative; aliquots can be stored frozen at -20°C to preserve activity across many freeze-thaw cycles. By labeling the Arp2/3 complex, the reagent is commonly deployed to investigate lamellipodia protrusion, invadopodia assembly, and actin-driven membrane trafficking in cell migration, and the recombinant production approach delivers consistent lot-to-lot performance for reproducible immunolabeling in fixed cells and tissue sections.