Anti-p150 (PIK3R4) Antibody

Raised in rabbit against the p150 regulatory subunit of phosphoinositide 3-kinase, this unconjugated polyclonal reagent from Antibodies.com targets PIK3R4 (also known as VPS15), a ~150 kDa scaffold kinase that partners with VPS34/PIK3C3 to nucleate autophagosome formation and to coordinate endosomal membrane trafficking in mammalian cells.

Supplied as 100 µl of antiserum, the antibody is validated for Western Blot, Immunohistochemistry, and Immunofluorescence applications on human samples. Researchers can use it to probe endogenous p150 expression in cell lysates, fixed tissue sections, and cultured cells, taking advantage of the polyclonal format to recognize multiple epitopes on the target protein.

PIK3R4 sits at the interface of mTORC1 nutrient sensing, phosphatidylinositol-3-phosphate lipid signaling, and selective autophagy, making this Primary Antibodies reagent useful for studies of vesicular transport, mitophagy, and signaling cross-talk in cancer biology, neurodegeneration, and metabolic disease models where autophagic flux is altered.