Anti-p130 Cas (Ab-410) Antibody

Manufactured by Antibodies.com, this affinity-purified reagent is a rabbit polyclonal IgG raised against a synthetic non-phosphopeptide derived from human p130 Cas in the region surrounding the tyrosine 410 phosphorylation site (G-V-T-A-V), enabling detection of total endogenous BCAR1/p130 Cas protein. Supplied at 50 µL per vial as an unconjugated antiserum at a concentration of 1.0 mg/mL, it is formulated in phosphate-buffered saline (without Mg²⁺ and Ca²⁺), pH 7.4, containing 150 mM NaCl, 0.02% sodium azide and 50% glycerol. The antibody is validated for Western blotting (WB) and immunohistochemistry (IHC) applications and has been confirmed to react with human and mouse samples. The product is shipped on cold packs at 4 °C and should be aliquoted upon arrival and stored at -20 °C, with repeated freeze/thaw cycles avoided to preserve activity. Recommended for research use only, this polyclonal reagent offers a robust tool for laboratories investigating Cas-family signalling, cell adhesion and mechanotransduction pathways.