Anti-p-Tau Antibody

Studying tauopathies such as Alzheimer's disease requires reagents that distinguish phosphorylated Tau from the unmodified protein. The Antibodies.com Anti-p-Tau antibody is a rabbit polyclonal reagent raised against the phosphorylated form of this microtubule-associated protein, supporting work that maps how abnormal phosphorylation drives tangle formation in neurons and how disease-linked modifications spread across brain regions.

Supplied as an unconjugated 100 µl volume, the antibody is validated for Western Blot, Immunohistochemistry, and Immunofluorescence workflows on human samples. Polyclonal reactivity broadens epitope coverage relative to monoclonal alternatives, which is useful when probing multiple phosphorylation sites. The unconjugated format leaves reporter choice open, from HRP and biotin secondaries to fluorophore conjugates for immunofluorescence imaging of cultured cells and fixed tissue sections.

Practical handling notes: aliquot on first use to limit freeze-thaw cycles, store refrigerated protected from light, and observe the printed shelf life. Sodium azide should be avoided in preparations intended for live-cell work or HRP-coupled detection, as it inactivates horseradish peroxidase and interferes with downstream enzymatic steps.