Anti-ORC2 Antibody

Origin Recognition Complex subunit 2 is a core component of the six-subunit ORC complex that marks replication origins and licenses chromosomal DNA for the initiation of S-phase. The polyclonal rabbit antibody raised against this target, supplied by Antibodies.com as 100 µl of unconjugated antiserum, supports Western blot and immunohistochemistry workflows on human samples and enables studies of replication licensing, cell-cycle entry, and the deregulation of origin firing observed in many tumor types. Researchers apply the reagent to investigate how ORC2 contributes to genome stability, chromatin organization at origins, and the crosstalk between replication timing and transcription in actively dividing cells.