Anti-OPRK1 Antibody

Produced in rabbit as an unconjugated IgG, this polyclonal reagent from Antibodies.com targets the kappa opioid receptor encoded by OPRK1, a G protein-coupled receptor implicated in nociception, reward circuitry, and stress responses. The antibody is validated for Western blot (WB) analysis of human, mouse, and rat samples, making it suitable for comparative neuroscience and receptor signaling studies where cross-species detection is needed. Each vial is supplied as 50 µl of liquid stock, stored under standard short-term refrigerated conditions to preserve IgG activity through repeated freeze-thaw cycles. Researchers commonly apply the reagent to membrane preparations from brain tissue or transfected cell lines expressing tagged OPRK1 constructs, with detection typically performed using HRP-conjugated secondary antibodies and chemiluminescent substrates. Intended for research use only, the product supports investigations into opioid receptor pharmacology, dynorphin signaling pathways, and behavioral models of analgesia or addiction.