Anti-OGT Antibody

The O-linked N-acetylglucosamine (GlcNAc) transferase (OGT) is a key enzyme that catalyzes the addition of O-GlcNAc to serine and threonine residues on numerous nuclear and cytoplasmic proteins. It plays essential roles in nutrient sensing, insulin signaling, transcription regulation, and cellular stress response pathways.

This rabbit polyclonal antibody from Antibodies.com targets endogenous OGT and is validated for Western blot (WB) and immunohistochemistry (IHC) workflows. It cross-reacts with Human, Mouse, and Rat samples, providing flexibility for studies spanning cell biology, metabolism, and signal transduction research across multiple model systems.

Supplied as 50 µL of unconjugated IgG in a polyclonal format, the reagent fits standard immunodetection protocols. Researchers apply it to investigate O-GlcNAcylation dynamics, glycosylation crosstalk with phosphorylation, and the involvement of OGT in diabetes, neurodegeneration, and cancer biology.