Anti-Oct-1/POU2F1 Antibody

POU2F1 (also called Oct-1) is a ubiquitously expressed POU-homeodomain transcription factor that recognizes the octamer DNA motif ATGCAAAT and regulates transcription of genes involved in immune function, histone biosynthesis, and snRNA production. This rabbit polyclonal reagent was raised against the Oct-1/POU2F1 protein and is supplied at 1 mg/ml in PBS with 0.1% sodium azide and 50% glycerol, packaged as a 100 µl vial. Validated for Western blot and immunohistochemistry workflows, the antibody shows reactivity with human, mouse, and rat samples, supporting cross-species studies of transcription factor expression in lymphoid tissues and cultured cell lines. Researchers apply this reagent to investigate B-cell signaling, herpes simplex and adenovirus promoter regulation, and stress-responsive gene programs where Oct-1 cooperates with other POU factors. The unconjugated format allows flexible pairing with secondary detection reagents of choice. Store aliquots refrigerated and protect from light to preserve activity across freeze-thaw cycles. Produced by Antibodies.com as a primary antibody reagent for research use only.