Anti-OAZ1 Antibody

OAZ1 (Ornithine Decarboxylase Antizyme 1) is a negative regulator of polyamine biosynthesis that binds and targets ornithine decarboxylase for proteasomal degradation, making this polyclonal reagent from Antibodies.com useful for studying feedback control of cellular polyamine pools, cell proliferation, and antizyme-mediated tumor suppressor pathways. The rabbit antibody is unconjugated and has been validated for Western blot detection of the endogenous OAZ1 target in human, mouse, and rat samples. The antiserum is supplied as 100 µl of a 1 mg/ml stock in phosphate buffered saline (PBS) containing 0.05% sodium azide at approximately pH 7.3, ready to dilute into standard immunoblotting workflows. Because the host species is rabbit, the reagent pairs cleanly with anti-rabbit secondary antibodies conjugated to HRP, fluorophores, or biotin for chemiluminescent, fluorescent, or chromogenic Western blot readout. Researchers investigating polyamine metabolism, ODC regulation, or changes in antizyme expression during cellular stress, differentiation, and proliferation can use this antibody to probe endogenous OAZ1 protein levels in whole-cell lysates, membrane fractions, and tissue extracts.