Anti-NVL Antibody

NVL (Nuclear VCP-Like protein) is a nuclear AAA-ATPase that plays a central role in ribosome biogenesis and the assembly of the 60S ribosomal subunit. This unconjugated rabbit polyclonal antibody from Antibodies.com is raised against NVL and validated for Western Blot detection. The reagent cross-reacts with human, mouse, and rat samples, supporting comparative expression studies across species in a single workflow.

Supplied at 1 mg/ml in PBS with 0.1% Sodium Azide and 50% Glycerol, the 100 µl vial is formatted for routine blotting experiments. The polyclonal format provides recognition of multiple epitopes on the target, which is useful when probing expression patterns, splice variants, or post-translational modifications. Store at -20°C; aliquot to minimize freeze-thaw cycles and preserve binding activity over multiple uses.

Researchers commonly apply this antibody to investigate NVL function in pre-rRNA processing, ribosome assembly, and stress responses, as well as its emerging links to hepatocellular carcinoma and other cancers where dysregulated ribosome biogenesis contributes to tumor growth.