Anti-NUP98 Antibody [2H10]

The Anti-NUP98 Antibody [2H10] from Antibodies.com is a rat monoclonal IgG2c reagent targeting Nucleoporin 98 (NUP98), a structural constituent of the nuclear pore complex involved in nucleocytoplasmic trafficking, mRNA export, and mitotic checkpoint control. Clone 2H10 has been widely referenced in published literature exploring NUP98 fusion oncoproteins that drive acute myeloid leukemia, as well as in cell-cycle investigations of nuclear envelope disassembly during mitosis.

This unconjugated antibody is supplied as a 100 µg liquid aliquot and is validated for Western blot (WB), dot blot (DB), immunocytochemistry/immunofluorescence (ICC/IF), ELISA, and immunoprecipitation (IP). The reagent cross-reacts with Human, Mouse, Rat, and Schizosaccharomyces pombe samples, supporting comparative studies between mammalian systems and fission yeast models of nuclear transport and pore biogenesis.

For optimal stability, store frozen at -20 °C, avoid repeated freeze-thaw cycles, and centrifuge briefly before opening. Intended for research use only; not for diagnostic or therapeutic applications.