Anti-NUP50 Antibody

The NUP50 target, also known as Nuclear pore complex protein Nup50 or NPAP60L, is a peripheral component of the nuclear pore complex that docks importin-α/β cargo complexes at the nucleoplasmic face and accelerates their release into the nucleoplasm. This unconjugated rabbit polyclonal reagent from Antibodies.com is raised against the human NUP50 sequence and validated for western blot and immunohistochemistry workflows on human samples, supporting studies of nucleocytoplasmic trafficking, mitotic nuclear envelope reformation, and importin-mediated cargo shuttling.

Each vial contains 100 µL of affinity-purified antisera in a format suited to standard SDS-PAGE transfer and paraffin-embedded section staining protocols used to probe NPC assembly state and nuclear import kinetics in fixed cells and tissue. The polyclonal format recognizes multiple epitopes across the NUP50 protein, which helps maintain signal where post-translational modifications or alternative splicing variants matter, and the unconjugated preparation lets researchers couple it to their preferred HRP, fluorophore, or biotin reporter for downstream detection.