Anti-NUMBL Antibody

Raised in rabbit and supplied as 50 µl of unconjugated IgG, this polyclonal reagent from Antibodies.com is configured for western blot detection of NUMBL in human samples. NUMBL (Numb-like protein) is a cytoplasmic adaptor that participates in clathrin-mediated endocytosis and modulates Notch receptor trafficking, so clean immunoblotting of endogenous NUMBL is a common entry point for studies of asymmetric cell division and fate specification.

The unconjugated format leaves the choice of reporter open, allowing the antibody to be paired with HRP- or fluorophore-conjugated secondary antibodies depending on the detection chemistry of a given blot. Polyclonal IgG raised against the human target provides broad epitope coverage, which can be useful when probing lysates where post-translational modification or splice variation might mask individual epitopes. Each vial of 50 µl is intended for research use and is sufficient for several rounds of probing at typical working dilutions.

Key specifications include rabbit host, polyclonal clonality, IgG isotype, unconjugated conjugate, human reactivity, and western blot application. For handling, the antibody should be stored refrigerated and protected from light, with aliquoting recommended to limit freeze-thaw cycles that can degrade binding activity over time.