Anti-NUMBL Antibody

This polyclonal antibody from Antibodies.com targets NUMBL (Numb-like protein), a cytoplasmic signaling protein involved in cell fate determination and Notch pathway regulation. NUMBL functions as a homolog of NUMB and participates in clathrin-mediated endocytosis, ubiquitination, and neurite outgrowth during neuronal differentiation. The reagent is raised in Rabbit, isotype IgG, and is supplied unconjugated in a 200 µl vial ready for Western blot (WB) workflows on human samples. Investigators studying neurogenesis, asymmetric cell division, and Notch receptor trafficking use NUMBL detection to probe neural progenitor populations and post-mitotic neuron lysates. For short-term storage, refrigerate at 4 °C; aliquot before freezing to preserve activity and avoid repeated freeze-thaw cycles. Intended for research use only.