Anti-NUMBL Antibody

NUMBL (NUMB-like endocytic adaptor protein) is a cytoplasmic adaptor that participates in Notch signaling and contributes to cell-fate decisions during differentiation. This unconjugated rabbit polyclonal reagent from Antibodies.com was raised against NUMBL and is affinity-purified for use in Western blot workflows on human samples. Supplied as 100 µl of ready-to-titrate IgG, the antibody recognizes endogenous NUMBL protein and is validated for immunoblotting of lysates prepared from cultured mammalian cells. Researchers studying neuronal progenitor maintenance, asymmetric division, or Notch pathway modulation will find this reagent useful for confirming expression changes and tracking NUMBL levels across differentiation time courses. The polyclonal format allows recognition of multiple epitopes, supporting consistent detection even if minor conformational changes occur. Aliquot upon arrival and store refrigerated at 4 degrees C to preserve activity across multiple experiments; avoid repeated freeze-thaw cycles. For research use only.