Anti-NUDT1 Antibody

The NUDT1 protein (Nudix Hydrolase 1, also called MTH1) is a sanitizing enzyme that hydrolyzes oxidized purine nucleoside triphosphates such as 8-oxo-dGTP and 2-OH-dATP, helping prevent their incorporation into DNA. This unconjugated rabbit polyclonal reagent from Antibodies.com is raised against NUDT1 and validated for Western Blot detection across Human, Mouse, and Rat samples.

Supplied as 100 µL of antibody at 1 mg/ml in PBS with 0.1% Sodium Azide and 50% Glycerol as a cryoprotectant, the reagent should be stored frozen in aliquots to limit freeze-thaw cycles and protect from light. Researchers investigating oxidative DNA damage repair, nucleotide pool sanitization, and cancer cell survival under oxidative stress use this polyclonal reagent to probe endogenous NUDT1 expression levels in cell lysates and tissue homogenates by Western Blot.

The polyclonal format offers broader epitope coverage than monoclonal alternatives, supporting detection of multiple NUDT1 isoforms when the target is present at low abundance.