Anti-nucleoporin p62 Antibody

This rabbit polyclonal antibody from Antibodies.com targets nucleoporin p62 (NUP62), an essential structural component of the central transport channel within the nuclear pore complex. NUP62 mediates nucleocytoplasmic trafficking of proteins and RNA, participates in mitotic spindle assembly, and is increasingly studied for its altered expression and post-translational modification in cancers of the breast, lung, and central nervous system, as well as in certain neurodegenerative proteinopathies such as primary biliary cirrhosis and specific tauopathies.

Supplied as 100 µl of unconjugated antiserum, the reagent is validated for Western blot, immunohistochemistry on formalin-fixed paraffin-embedded tissue, and immunofluorescence imaging of cultured human cells. The polyclonal response recognizes multiple epitopes across the human NUP62 protein, which can improve detection sensitivity in samples where the target is expressed at low abundance or partially degraded. Host species is rabbit, clonality is polyclonal, and the product is intended for research use only in studies of nuclear envelope biology, cell division, and transport regulation.