Anti-NTF3 Antibody

This rabbit polyclonal antibody from Antibodies.com targets Neurotrophin 3 (NTF3), a secreted growth factor of the neurotrophin family that supports the development and maintenance of peripheral and central neurons through TrkB and TrkC receptor signaling. Supplied as an unconjugated reagent in a 100 µl vial, the antibody is validated for Western blot and immunohistochemistry workflows on human samples. NTF3, also referred to as NT-3, is encoded on chromosome 12p13 and is expressed across neuronal and non-neuronal tissues including smooth muscle and epithelial compartments.

The polyclonal format yields multiple epitope recognition on the mature neurotrophin and its precursor proNTF3, giving broader coverage when probing tissue lysates or fixed sections. Laboratories investigating sympathetic neuron survival, dorsal root ganglia development, or neurotrophic signaling pathways use this reagent to detect endogenous NTF3 levels. The unconjugated format allows direct pairing with custom secondary detection chemistries, fluorophores, or HRP enzymes as required by a given protocol, and it is compatible with chromogenic IHC, immunofluorescence, and standard Western blot detection.

For handling, the antiserum should be kept refrigerated and protected from light; aliquoting upon first use and avoiding repeated freeze-thaw cycles preserves antibody activity over months. This reagent is supplied at a working dilution suitable for direct optimization on the user's sample set.