Anti-NSUN6 Antibody

This unconjugated rabbit polyclonal reagent targets NSUN6, a cytoplasmic RNA methyltransferase that catalyzes 5-methylcytosine formation at position 72 of select tRNAs and contributes to translational regulation. Manufactured by Antibodies.com, the antibody is supplied as 100 µl of polyclonal IgG raised in rabbit and is validated for Western blot (WB) and immunoprecipitation (IP) workflows with demonstrated reactivity against human and mouse samples.

Researchers investigating post-transcriptional tRNA modification, RNA methyltransferase biology, or NSUN6-associated pathways can use this reagent to immunoprecipitate endogenous NSUN6 complexes from cell lysates or to detect the protein across tissues by Western blot. The unconjugated format gives laboratories flexibility to pair the antibody with their preferred HRP-, fluorophore-, or biotin-conjugated secondary reagents, and the polyclonal formulation provides an epitope-spread advantage for IP capture of native NSUN6.

For best stability, aliquot the reagent into single-use volumes to limit freeze-thaw cycles and store frozen for long-term preservation; working aliquots can be refrigerated short-term. Because performance depends on lysate preparation, fixation, and detection chemistry, researchers should titrate the reagent within their own Western blot and immunoprecipitation protocols.