Anti-NRP1 Antibody

Neuropilin-1 (NRP1), a multifunctional transmembrane glycoprotein that serves as a co-receptor for vascular endothelial growth factor (VEGF) and class III semaphorins, can be reliably detected in Human, Mouse, and Rat samples using this rabbit polyclonal reagent from Antibodies.com. NRP1 participates in angiogenesis, vascular permeability, axon guidance, and immune cell regulation, including the modulation of regulatory T cell activity.

Supplied as 50 µl of unconjugated IgG, the antibody is validated for Western blot workflows on cell and tissue lysate preparations. The polyclonal format provides recognition across multiple epitopes on NRP1, supporting consistent band detection in studies of tumor vascularization, neurodevelopment, and VEGF-mediated signaling pathways.

Researchers investigating endothelial cell behavior, neuronal patterning, semaphorin pathway activity, or immunomodulatory mechanisms commonly select this reagent for expression profiling and mechanistic work. Rabbit host and unconjugated format allow flexible pairing with secondary detection reagents such as HRP- or fluorophore-conjugated anti-rabbit IgG for chemiluminescent or fluorescent Western blot readouts.