Anti-NRG4 Antibody

Raised in rabbit against the neuregulin 4 (NRG4) ligand, this polyclonal antibody from Antibodies.com is validated for Western blot detection of the endogenous protein across human, mouse, and rat samples. Neuregulin 4 is a membrane-tethered EGF-family ligand predominantly expressed in brown adipose tissue and pancreatic beta cells, where it signals through ERBB4 to influence hepatic lipid metabolism, energy expenditure, and glucose homeostasis. The unconjugated reagent is supplied as 100 µL of a 1 mg/ml stock in phosphate buffered saline (PBS) containing 0.05% sodium azide at approximately pH 7.3, ready to dilute directly into standard WB workflows without buffer exchange. Researchers investigating NAFLD pathogenesis, adipocyte-hepatocyte crosstalk, or ERBB receptor signaling frequently select this reagent because its broad species reactivity supports parallel analysis of rodent disease models and human biopsy material on the same blot. The antibody is provided in a single-use vial format, intended for research use only, and should be stored refrigerated to preserve activity across repeated experiments.