Anti-NRG3 Antibody

NRG3 (Neuregulin 3) is a member of the neuregulin family of EGF-like signaling ligands, playing critical roles in nervous system development, neuronal differentiation, and synaptic plasticity. This rabbit polyclonal antibody targets the human NRG3 protein and is supplied by Antibodies.com as an unconjugated primary antibody in a 100 µl vial format.

The reagent is validated for Western blot (WB) and immunohistochemistry (IHC) applications, supporting detection of endogenous NRG3 expression in human tissue sections and cell lysates. Because NRG3 signals principally through ErbB4 receptor tyrosine kinase activation, researchers use this antibody to investigate neuregulin-ErbB signaling pathways in neurobiology, schizophrenia susceptibility studies, and emerging oncology research where NRG3 dysregulation has been implicated in breast and pancreatic cancers.

Polyclonal antibodies recognize multiple epitopes across the target protein, offering broader recognition of NRG3 isoforms and increased tolerance for minor sample variations. The unconjugated format provides flexibility in choosing detection chemistries: HRP, fluorescent, or biotin-based secondary systems can be paired with the reagent depending on experimental design. For long-term storage, aliquot the antibody and keep it frozen to preserve activity, avoiding repeated freeze-thaw cycles. This product is intended for research use only.