Anti-NRG1 Antibody

This polyclonal antibody from Antibodies.com targets Neuregulin 1 (NRG1), a membrane-bound and secreted EGF-family ligand that signals through ErbB3 and ErbB4 receptor tyrosine kinases. Raised in rabbit and supplied at 1 mg/ml in PBS with 0.1% sodium azide and 50% glycerol, the reagent is validated for Western blot (WB) and immunohistochemistry (IHC) workflows across human, mouse, and rat samples.

NRG1 research spans developmental neuroscience, Schwann cell myelination, cardiac development, and oncology. Investigators studying ErbB receptor signaling use this unconjugated antibody to probe ligand expression in tissue sections and to detect endogenous protein in lysates. NRG1 fusion transcripts and overexpression have been reported in subsets of lung adenocarcinoma and other solid tumors, making this reagent relevant to studies of HER pathway dysregulation.

Each vial contains 100 µl of the 1 mg/ml stock. The polyclonal format offers broader epitope coverage than monoclonal alternatives, useful when probing multiple NRG1 isoforms. Store aliquots frozen at -20°C or colder, avoid repeated freeze-thaw cycles, and protect from light to preserve working dilutions. For research use only; not intended for diagnostic or therapeutic applications.