Anti-Nrf2 Antibody

This polyclonal primary antibody from Antibodies.com specifically recognizes Nrf2 (Nuclear factor erythroid 2–related factor 2), the basic leucine zipper transcription factor that drives the cellular antioxidant response through antioxidant response element (ARE)-driven gene expression. Produced in rabbit and supplied unconjugated in a 100 µl volume, it is validated for Western blot and ELISA workflows across human, mouse, and rat samples. The reagent supports cross-species studies of oxidative stress, phase II detoxification enzyme induction, and the KEAP1-Nrf2 signaling axis that governs cytoprotective gene expression under electrophilic or xenobiotic challenge. The polyclonal format increases the likelihood of detecting multiple Nrf2 epitopes, useful for monitoring KEAP1-mediated stabilization, nuclear translocation, and changes in total Nrf2 abundance following pharmacological or oxidative activation of the pathway.