Anti-NRAS Antibody

NRAS is a member of the RAS oncogene family and encodes a small GTPase that regulates cell proliferation, differentiation, and survival signaling through the MAPK/ERK cascade. This unconjugated rabbit polyclonal antibody, supplied by Antibodies.com, is raised against NRAS and validated for Western blot (WB) and immunohistochemistry (IHC) applications on human samples.

Delivered as a 100 µl vial of polyclonal antiserum, the reagent supports detection of endogenous NRAS protein in cell lysates and formalin-fixed tissue sections. Investigators of melanoma, colorectal cancer, and other NRAS-driven malignancies rely on isoform-specific reagents such as this to study mutational hotspots such as codon Q61 and to characterize downstream RAF-MEK-ERK signaling in tumor biology. Store refrigerated in working aliquots to limit repeated freeze-thaw cycles of the antiserum and preserve binding activity across multiple experiments.