Anti-NR1H4 Antibody

Rabbit polyclonal IgG antibody raised against the nuclear receptor NR1H4 (also known as FXR, the farnesoid X receptor), supplied by Antibodies.com as an unconjugated 50 µl reagent validated for western blot applications. The antibody recognizes human, mouse, and rat NR1H4, a ligand-activated transcription factor that functions as the principal intracellular sensor for bile acids and regulates glucose, lipid, and cholesterol homeostasis in enterohepatic tissue. Provided as a liquid aliquot in a vial, the reagent is suitable for detecting endogenous FXRα in lysates prepared from liver, intestine, kidney, and adrenal samples, where the receptor migrates as a ~70 kDa band in standard SDS-PAGE western blot workflows. Store aliquots frozen and protect from light; the polyclonal format offers broad epitope coverage for probing full-length receptor isoforms and post-translational modifications.