Anti-NR1H4 Antibody

Produced in Rabbit and supplied by Antibodies.com as an unconjugated IgG preparation, this polyclonal antibody detects NR1H4 (Farnesoid X Receptor, FXR), a ligand-activated nuclear receptor that functions as a primary bile acid sensor and regulates transcription of genes involved in bile acid synthesis, cholesterol metabolism, and glucose homeostasis. The reagent is validated for Western blot (WB) applications and shows cross-reactivity with Human, Mouse, and Rat samples, supporting comparative work across mammalian model systems.

The 100 µl liquid aliquot is suitable for multiple immunoblotting experiments, and the polyclonal format provides broader epitope coverage for detecting endogenous receptor levels in tissue and cell lysates. Researchers studying hepatic signaling, enterohepatic circulation, nuclear receptor pharmacology, or metabolic disease pathways will find this reagent useful for characterizing FXR expression and activation state under different physiological and pharmacological conditions.