Anti-NPY2-R Antibody

This polyclonal antibody from Antibodies.com targets the Neuropeptide Y receptor Y2 (NPY2R), a G-protein coupled receptor central to appetite regulation, energy homeostasis, and synaptic signaling in the central nervous system. Raised in rabbit, the unconjugated reagent is supplied as 100 µl and is validated for western blot (WB), immunofluorescence (IF), and ELISA applications.

Reactivity spans Human, Mouse, and Rat species, allowing cross-species comparison in metabolic, neuroendocrine, and behavioral studies. NPY2R is widely expressed in hypothalamus, hippocampus, and select peripheral tissues, where it modulates cellular responses to neuropeptide Y and peptide YY ligands.

Researchers apply this antibody to map receptor distribution in brain sections, profile NPY2R levels in tissue lysates, and characterize neuropeptide pathways relevant to feeding behavior, anxiety, and memory. Its polyclonal format increases the likelihood of recognizing multiple epitopes on the receptor, supporting both qualitative imaging in immunofluorescence workflows and semi-quantitative western blot analyses.