Anti-NPY1R Antibody

NPY1R (Neuropeptide Y Receptor Y1) is a class A G protein-coupled receptor that mediates central and peripheral signaling by neuropeptide Y, peptide YY, and pancreatic polypeptide. The unconjugated rabbit polyclonal antibody from Antibodies.com is raised against the human receptor and validated for Western blot and immunohistochemistry on human and mouse samples, supporting studies of appetite regulation, anxiety, memory, vascular tone, and cardiac signaling pathways.

Supplied as 100 µl of antiserum, the reagent is suitable for probing tissue lysates and fixed tissue sections, with dual-species reactivity consistent with strong sequence conservation within the third intracellular loop and C-terminal tail epitopes. Investigators working on hypothalamic feeding circuits, stress-responsive brain regions, or smooth muscle contractility can use this antibody to map receptor distribution and quantify changes in expression across disease models of obesity, hypertension, and neurodegeneration.