Anti-NPTX2 Antibody

This unconjugated rabbit polyclonal IgG reagent from Antibodies.com targets NPTX2 (Neuronal Pentraxin 2, also known as Narp), a secreted glycoprotein expressed at excitatory synapses where it contributes to AMPA receptor clustering and activity-dependent synaptic plasticity. Produced in rabbit and affinity-purified, the antibody is supplied as 100 µl of liquid in a single-use vial and is validated for western blot (WB) and immunohistochemistry (IHC) workflows on human tissue sections and lysates. Researchers studying Parkinson's disease, Alzheimer's-related synaptic dysfunction, glioma biology, or activity-regulated neuronal remodeling use NPTX2 as both a synaptic marker and a candidate biomarker, since circulating levels in cerebrospinal fluid and serum have been investigated as indicators of neurodegeneration and tumor progression. The antibody does not require a secondary-conjugate step and is intended for research use only, supporting both chromogenic and fluorescence-based detection in fixed and frozen preparations.