Anti-NPM3 Antibody

NPM3 (Nucleophosmin 3) is a histone chaperone of the nucleophosmin/nucleoplasmin family, and this polyclonal antibody from Antibodies.com is raised in rabbit against the human protein for use in western blot and immunohistochemistry workflows. Supplied as 100 µl in a vial format, the unconjugated reagent allows flexible pairing with HRP-, fluorophore-, or biotin-conjugated secondaries. The antibody recognizes endogenous NPM3, which localizes to nucleoli and participates in chromatin remodeling, ribosome biogenesis, and early embryonic chromatin programming. Validated reactivity with human samples supports studies of nucleolar architecture, NPM family interactions in stem cell models, and differential expression analyses in fixed tissue sections. Researchers applying this reagent should anticipate a strong nuclear staining pattern characteristic of nucleolar antigens, with signal intensity that can be boosted using tyramide signal amplification when higher sensitivity is required.