Anti-NPC2 Antibody

Raised in rabbit, this unconjugated polyclonal antibody specifically recognizes NPC2 (Niemann-Pick C2 protein), a small soluble lysosomal glycoprotein that binds cholesterol with high affinity and hands it off to NPC1 inside late endosomes. Antibodies.com supplies the reagent as a 100 µl aliquot validated for western blot, immunohistochemistry, and immunofluorescence workflows against human, mouse, and rat samples. It is a useful tool for studies of intracellular lipid trafficking, lysosomal storage disorders such as Niemann-Pick disease type C, and the cellular mechanisms of cholesterol homeostasis. Because it is supplied unconjugated, researchers can match it to any secondary reporter of choice for chromogenic, fluorescence, or chemiluminescent readout in their own immunodetection protocols.