Anti-NPAS1 Antibody

NPAS1 (Neuronal PAS domain protein 1) is a brain-enriched member of the bHLH-PAS transcription factor family, where it has been studied for its role in neurogenesis and circadian rhythm regulation. This unconjugated rabbit polyclonal reagent, manufactured by Antibodies.com, was raised against NPAS1 and validated for western blot detection of the endogenous protein in human, mouse, and rat samples, with confirmed reactivity across all three species.

The antibody is supplied as a 100 µl liquid vial at 1 mg/ml in phosphate buffered saline (PBS) containing 0.05% sodium azide at approximately pH 7.2. The unconjugated format gives researchers flexibility to pair this reagent with a user-selected secondary reporter for western blot, immunofluorescence, or immunohistochemistry workflows. Aliquoting upon receipt is recommended to limit freeze-thaw exposure, and the vial should be stored refrigerated between uses.

Typical research applications include mapping NPAS1 expression in the central nervous system, examining its contribution to neural stem cell maintenance, and probing reported links between this bHLH-PAS factor and tumor suppression pathways in neural and glial models.