Anti-Notch 1 Antibody

Engineered for high specificity toward the Notch 1 receptor, this recombinant reagent from Antibodies.com is supplied as a ready-to-use liquid rabbit monoclonal antibody validated across multiple detection platforms. Each vial contains 50 µl of unconjugated antibody, formulated in TBS (pH 7.4) supplemented with 1% BSA and 40% glycerol, with 0.05% sodium azide included as a preservative to maintain stability during routine laboratory storage. The host species is rabbit, the clonality is monoclonal, and the antibody is of the IgG isotype, providing researchers with a consistent, single-epitope reagent suitable for reproducible assay development. The antibody has been validated for Western blotting (WB), immunocytochemistry/immunofluorescence (ICC/IF), immunohistochemistry (IHC), and flow cytometry (FC), supporting work ranging from cell lysate analyses to fixed-tissue imaging and surface/intracellular phenotyping of Notch 1–expressing populations. Reactivity has been confirmed against human and mouse samples, making the reagent a useful tool for translational projects, comparative studies in cell-line and primary-cell models, and investigations of Notch 1 signaling in development, stem-cell biology, and oncology research. The target, Notch 1 (also known as hN1, TAN1, or Neurogenic locus notch homolog protein 1), is a transmembrane receptor that mediates cell-fate decisions upon ligand binding, and detection of this protein is commonly performed using unconjugated primary antibodies followed by appropriate secondary reagents. Distributed by AFMS as part of the Antibodies.com Primary Antibodies portfolio, this Notch 1 antibody offers a balance of broad application coverage, validated species reactivity, and a recombinant monoclonal production format that helps ensure lot-to-lot consistency for laboratories running comparative or longitudinal studies.