Anti-NOSTRIN Antibody

NOSTRIN (Nitric Oxide Synthase Trafficking Inducer) is an F-BAR domain adaptor protein that drives the subcellular relocalization of endothelial nitric oxide synthase (eNOS) from the plasma membrane into intracellular vesicles, modulating nitric-oxide output in vascular endothelium. This unconjugated rabbit polyclonal IgG from Antibodies.com is raised against NOSTRIN and validated for Western blot detection of the endogenous target in human and mouse samples, supplied as a 200 µl liquid aliquot.

Investigators in vascular biology, angiogenesis, and cytoskeletal-membrane trafficking apply this antibody to immunoblot whole-cell lysates or tissue homogenates, probing for the ~58 kDa NOSTRIN band and monitoring its redistribution after VEGF stimulation, shear stress, or pharmacological eNOS modulation. For chemiluminescent readout, pair with an HRP-conjugated anti-rabbit secondary on PVDF or nitrocellulose membranes.

Store refrigerated and protected from light; aliquot to limit freeze-thaw cycles. This product is for research use only and is not intended for diagnostic applications.