Anti-NOS2 Antibody

This rabbit polyclonal primary antibody from Antibodies.com targets NOS2, the inducible isoform of nitric oxide synthase that catalyzes the conversion of L-arginine into nitric oxide and L-citrulline in response to inflammatory cytokines and microbial products. Researchers studying macrophage polarization, hepatic inflammation, septic shock, and nitrosative stress use this reagent to detect inducible nitric oxide synthase in tissue sections and cell lysates.

Supplied as a 200 µL aliquot of unconjugated IgG, the antibody is raised in rabbit and validated for western blot (WB), immunohistochemistry (IHC), immunofluorescence (IF), and flow cytometry (FC) on human samples. The target, NOS2, is a ~131 kDa protein expressed primarily in stimulated macrophages, neutrophils, and hepatocytes following induction by interferon-gamma, tumor necrosis factor, or lipopolysaccharide. For research use only; not for diagnostic or therapeutic applications.