Anti-NOP56 Antibody

This rabbit polyclonal antibody targets NOP56, a conserved nucleolar protein that forms part of the box C/D small nucleolar ribonucleoprotein (snoRNP) complex. NOP56 is essential for 2'-O-methylation of ribosomal RNA precursors and the maturation of the 60S ribosomal subunit, making it a useful marker for studies of ribosome biogenesis and nucleolar architecture.

Manufactured by Antibodies.com, the reagent is supplied as 50 µl of unconjugated IgG raised in rabbit and is validated for Western blot detection of the human, mouse, and rat orthologs. The polyclonal format provides recognition of multiple epitopes across the target, supporting reliable detection in cell lysate and tissue homogenate preparations. Typical research applications include characterization of ribosomal RNA processing pathways, investigation of nucleolar stress responses, and studies into conditions such as Treacher Collins syndrome, in which NOP56 function is genetically implicated.