Anti-NOLC1 Antibody

Raised in rabbit against nucleolar and coiled-body phosphoprotein 1, this polyclonal reagent targets a multifunctional scaffold protein that shuttles between the nucleolus and Cajal bodies and supports ribosomal RNA transcription and processing. Supplied by Antibodies.com as an unconjugated Ig preparation at 1 mg/ml in phosphate buffered saline with 0.05% sodium azide at approximately pH 7.2, the antibody is validated for Western blot detection and reacts with endogenous NOLC1 from human, mouse, and rat lysates. The 100 µl pack is suited to multiple membrane probing experiments, and the unconjugated format lets researchers couple their own reporter enzymes or fluorophores for chemiluminescent or imaging workflows downstream.

NOLC1 interacts with coilin and casein kinase II, making this antibody useful as a nucleolar marker in studies of ribosome biogenesis, cellular stress response, and nucleolar reorganization through the cell cycle. Polyclonal coverage across the protein aids detection of full-length and post-translationally modified forms of the target, supporting experiments that follow phosphorylation-dependent changes in NOLC1 localization or mobility.