Anti-Nogo-R Antibody

Manufactured by Antibodies.com, this Rabbit polyclonal reagent is raised against the Nogo Receptor (RTN4R) and is supplied as a 50 µl liquid aliquot at a concentration of 1 mg/ml. The antibody is unconjugated and is presented in PBS containing 0.1% Sodium Azide and 50% Glycerol as a stabiliser, making it ready to use directly in standard immunoassays. It is validated for Western Blot (WB) applications and has been confirmed to react with Human, Mouse, and Rat samples, supporting broad use across neuroscience and regenerative-biology research. The host species is Rabbit, the clonality is Polyclonal, and the reagent is intended for research use only. Recommended storage is at -20 °C for long-term stability, with the antibody shipped cold (typically on wet ice or blue ice) to preserve activity through transit. For Western Blot, working dilutions in the range of approximately 1:500–1:2000 are commonly used as a starting point, although optimal titres should be determined empirically for each lysate and detection system. The Nogo-R target, also known as NgR1, Nogo-66 receptor, NOGOR, or Reticulon-4 receptor, is a GPI-anchored cell-surface receptor that mediates axonal growth inhibition in the central nervous system and is widely studied in the context of neuronal injury, plasticity, and myelin-associated inhibition. As with all Antibodies.com primary antibodies, this polyclonal is affinity-purified to reduce background and is supplied with full traceability, allowing researchers to cite a defined immunogen and host combination in their methods sections. Whether your work focuses on spinal-cord injury models, oligodendrocyte biology, or signalling downstream of MAG and OMgp, this reagent offers a reliable, lot-controlled option for detecting endogenous Nogo-R protein by immunoblotting.