Anti-Nogo-R Antibody

Produced in rabbits, this unconjugated polyclonal reagent targets the Nogo receptor (Nogo-R/RTN4R), a GPI-anchored leucine-rich repeat protein that binds the inhibitory myelin ligands Nogo-A, MAG, and OMgp to constrain axon regrowth after CNS injury. The antibody is validated for western blot on samples from human, mouse, and rat origins, making it relevant to studies of spinal cord trauma, multiple sclerosis models, and developmental neurobiology. It is supplied as a 100µl volume at 1 mg/ml in PBS with 0.1% sodium azide and 50% glycerol, ready to dilute into standard immunoblotting buffers. Aliquot on arrival and store at -20°C to preserve activity through repeated freeze-thaw cycles; protect from light and avoid prolonged exposure to room temperature. From Antibodies.com, the reagent is intended for research use only in protein-level interrogation of Nogo-R signaling in neural repair and glial scarring research.