Anti-NOG Antibody

This polyclonal reagent targets Noggin (NOG), a secreted BMP antagonist central to neural patterning, chondrogenesis, and joint morphogenesis. Raised in rabbit, the IgG antibody is supplied unconjugated in a 200 µL vial and validated for Western blot detection of endogenous mouse and rat Noggin protein in tissue lysates and cell extracts.

The antibody recognizes the secreted homodimer form and has been used to study BMP pathway modulation in developing cartilage, neural tube, and osteoblast model systems. Compatible with standard SDS-PAGE workflows and chemiluminescent readouts, the reagent supports investigation of Noggin expression in developmental biology, musculoskeletal research, and tissue injury-response studies.

Working dilutions commonly start at 1:500 to 1:2000 for immunoblotting applications. Store the vial refrigerated at 4 °C and avoid repeated freeze-thaw cycles to preserve antibody activity. Each lot is affinity-purified and quality-tested by Antibodies.com to ensure reproducible specificity for the Noggin target across experimental replicates, with reactivity confirmed against mouse and rat samples.