Anti-NME1 Antibody

Produced by Antibodies.com, this rabbit polyclonal antibody recognizes NME1 (nucleoside diphosphate kinase 1, also known as NM23-H1), a well-characterized metastasis suppressor protein implicated in tumor progression, cell differentiation, and nucleotide metabolism. The unconjugated reagent is supplied in a 100 µl vial and validated for Western blot, immunohistochemistry, and immunofluorescence applications in human, mouse, and rat samples.

NME1 catalyzes gamma-phosphate transfer between nucleoside tri- and diphosphates and participates in G-protein signaling, apoptosis regulation, and DNA repair. Investigators use this polyclonal reagent to map NM23 family expression in melanoma and carcinoma models where reduced levels correlate with high metastatic potential, as well as to study basic cell biology and signal transduction pathways. Polyclonal recognition of multiple epitopes supports reproducible detection across tissue sections, cultured cells, and lysate preparations.

Recommended for research use only, the antibody should be stored refrigerated and handled with care to preserve activity across multiple freeze-thaw cycles. Pair it with an appropriate HRP- or fluorophore-conjugated secondary antibody for your specific detection platform.