Anti-NMDAε4 Antibody

Raised in rabbit against the NMDAε4 subunit (also designated GRIN2D), this unconjugated polyclonal antibody from Antibodies.com is supplied as 100 µL of liquid and is validated for western blot and ELISA workflows. NMDAε4 is a GluN2-family member of the ionotropic NMDA glutamate receptor, prominently expressed during early postnatal brain development with strong enrichment in the striatum, thalamus, and hippocampus, where it shapes slow-decaying excitatory currents and contributes to activity-dependent circuit maturation.

Reactivity with human, mouse, rat, and monkey orthologues enables cross-species studies of synaptic signaling, developmental neurobiology, and receptor pharmacology. The polyclonal format recognizes multiple epitopes on the target subunit, and the unconjugated formulation allows researchers to pair it with HRP, biotin, or fluorophore labels of their own choosing. Recommended applications include western blot analysis of membrane-enriched fractions prepared from neural tissue or transfected cell lines, alongside ELISA-based quantification of subunit levels in experimental samples.

Aliquot upon arrival to limit freeze-thaw cycles and keep refrigerated for routine short-term use; long-term storage at -20 °C is appropriate for projects extended over several months.