Anti-NMD3 Antibody

Targeting NMD3, a conserved ribosome biogenesis factor that serves as the nuclear export adapter for the 60S large ribosomal subunit, this unconjugated rabbit polyclonal primary antibody from Antibodies.com is raised against a target that shuttles pre-60S particles from the nucleolus through the nucleoplasm to the cytoplasm via the CRM1/XPO1 export pathway. NMD3 is subsequently released and recycled back to the nucleus, making it a key regulator of large-subunit assembly and nucleocytoplasmic transport.

Provided as 100 µl of IgG polyclonal antiserum in an unconjugated format, the antibody is validated for Western Blot detection in human and mouse samples. The unconjugated formulation allows laboratories to pair it with their preferred HRP, fluorescent, or alkaline phosphatase secondary detection systems depending on the experimental design. The polyclonal nature of the reagent broadens epitope coverage, supporting detection of the endogenous NMD3 protein across lysate preparations from cultured mammalian cells and tissue homogenates.

Suited to studies of ribosome assembly, translation regulation, and ribosome export trafficking, the reagent is provided for research use only. Store the vial refrigerated, protect from light where relevant to the chosen secondary workflow, and minimize repeated freeze-thaw cycles by aliquoting as needed for long-term use.