Anti-NKX2-5 Antibody

Affinity-purified in rabbits against the NKX2-5 homeodomain transcription factor, this unconjugated polyclonal reagent from Antibodies.com is supplied as 100 µl volumes validated for Western blot (WB) and immunofluorescence (IF) on human samples.

NKX2-5 (also called CSX) governs cardiac specification, heart morphogenesis, and the maintenance of cardiomyocyte identity, making it a primary target for researchers studying congenital heart defects, cardiac transcription factor networks, and the directed differentiation of pluripotent stem cells into functional cardiomyocytes. The polyclonal format recognizes multiple epitopes across the protein, supporting clear detection in both blotting and fixed-cell imaging workflows.

Used as a definitive nuclear marker of the developing and adult myocardium, the antibody supports studies in developmental biology, cardiology, and regenerative medicine. Its unconjugated presentation allows flexible pairing with HRP-, fluorophore-, or biotin-conjugated secondary antibodies to match diverse detection platforms.