Anti-NK-1R Antibody

Manufactured by Antibodies.com, this rabbit polyclonal reagent targets the Neurokinin-1 receptor (NK-1R), also referred to as TACR1, SPR, Substance-P receptor, TAC1R, and Tachykinin receptor 1. The antibody is supplied as a 50 µl liquid formulation at a concentration of 1 mg/mL in PBS containing 50% glycerol, 0.5% BSA, and 0.02% sodium azide, and it is unconjugated for maximum flexibility in downstream labelling workflows. It was raised against a synthetic peptide derived from the internal region of human NK-1R and subsequently affinity-purified from rabbit antiserum by affinity-chromatography using the epitope-specific immunogen, ensuring recognition of endogenous levels of the receptor. The host species is rabbit and the clonality is polyclonal, making it suitable for a broad range of detection platforms. Validated applications include Western blotting (WB), immunofluorescence (ICC/IF), and ELISA, with demonstrated cross-reactivity in human, mouse, and rat samples. For handling, the product is shipped at 4 °C; upon receipt, aliquots should be stored at -20 °C, avoiding repeated freeze/thaw cycles, with a recommended shelf life of approximately one year under these conditions. Researchers studying G-protein-coupled signalling, neuropeptide binding, pain pathways, or inflammatory responses will find the reagent a reliable tool for characterising NK-1R expression across multiple model systems.