Anti-NIT2 Antibody

Antibodies.com offers this rabbit polyclonal antibody targeting the human NIT2 protein, a cytoplasmic omega-amidase enzyme belonging to the nitrilase family. NIT2 catalyzes the hydrolysis of alpha-ketoglutaramate to alpha-ketoglutarate and ammonia, a key step in the kynurenine pathway of tryptophan catabolism connected to NAD+ biosynthesis. The reagent is supplied as a 50 µl aliquot of affinity-purified IgG in unconjugated format, validated for western blot and immunohistochemistry on human samples. Investigators working on metabolic enzyme regulation, hepatocyte function, or tumor biology can use this antibody to detect endogenous NIT2 expression in cell lysates and paraffin tissue sections. Store at -20 °C in small working aliquots to minimize freeze-thaw cycles and preserve antibody activity across multiple experiments.