Anti-NIT2 Antibody

The polyclonal rabbit antibody targets NIT2 (nitrilase family member 2), a cytoplasmic hydrolytic enzyme that catalyzes the conversion of alpha-ketoglutaramate to alpha-ketoglutarate and ammonia in the nitrogen metabolism pathway. This unconjugated IgG reagent from Antibodies.com is supplied as 200 µl of ready-to-use solution, validated for Western blot and immunohistochemistry on human-derived samples.

Investigators working in tumor biology, hepatocyte function, glutamine metabolism, or hepatocellular carcinoma research use this reagent to detect endogenous NIT2 expression in cell lysates and formalin-fixed tissue sections. NIT2 has been characterized as a candidate tumor suppressor with documented roles in cell proliferation and nitrogen disposal pathways, making the antibody a useful tool for studies of apoptosis and metabolic regulation. The polyclonal host rabbit IgG format provides broad epitope recognition for reliable signal generation across immunoblotting and chromogenic tissue staining workflows.

For best results, store at -20 °C and avoid repeated freeze-thaw cycles by preparing working aliquots before first use. The unconjugated format allows flexible selection of secondary detection reagents for fluorescence, chromogenic, or chemiluminescent readouts. Each vial is intended for research use only and has been quality controlled for the listed applications.